Mary Lou Mastro


Meet Mary Lou Mastro, MS, RN, FACHE.

Mary Lou served as CEO of the South Region of NorthShore – Edward-Elmhurst Health, which includes Edward Hospital, Elmhurst Hospital, and Linden Oaks Behavioral Health until her retirement on Dec. 31, 2022. She served as System Chief Executive Officer (CEO) of Edward-Elmhurst Health since 2016.

With more than 45 years working in hospitals and health systems, Mary Lou made it her mission to transform the healthcare experience by making it safe, seamless and personal. As CEO, Mary Lou led the EEH merger with NorthShore, helping to enable the creation of NorthShore – Edward Elmhurst Health as a regional destination for differentiated vibrant, community connected healthcare.

Mary Lou earned her bachelor’s degree in nursing from DePauw University and her master’s degree from Rush University in Chicago. Among many honors, she received the Rotary Club of Naperville’s Paul Harris Community Service award for advocacy of mental health awareness and transforming Linden Oaks into a regional resource for mental healthcare. She is past Chairman of the American Hospital Association Governing Council for Psychiatric and Substance Abuse Services and is a past Trustee on the Illinois Hospital Association Board.

She served on the Regional Policy Board for the American Hospital Association and as board member of the Boys & Girls Club of Chicago and the Kennedy Forum Leadership Council. She is a Fellow in the American College of Healthcare Executives.

Number of Posts: 49
Contributor Since: 4/28/2017
Favorite Category: Popular
Lou MemorialDaycrop

Memorial Day remembrance

May 25, 2022
Let’s take a few moments to remember those who have died for our country so we can live free.
Lou pharmacy group photo crop

Let’s embrace our differences

October 25, 2021
October is Global Diversity Awareness Month. It’s a good reminder to open our minds to the diversity in our community and take a deeper look at how...
mother daughter talk

Let’s talk openly about mental health, it matters to all of us

May 05, 2021
Mental health care is as vital as primary care and emergency care.

One of the top health systems in the country is in your back yard

April 27, 2021
You’re getting the best of the best at Edward-Elmhurst Health.

Let’s hear it for our rehabilitation specialists!

September 22, 2020
Rehabilitation specialists play a crucial role in our patients’ quality of life.

A message from our System CEO: Wear a mask

August 05, 2020
I believe it is important to share some of what we’ve learned at Edward-Elmhurst Health during the past six months.
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