Should pregnant women get the COVID-19 vaccine?

February 12, 2021 | by Kimberley Darey, M.D.
Categories: Healthy Driven Moms

Vaccinations during pregnancy are important and common. If you are pregnant or breastfeeding, you are likely familiar with vaccines that are typically recommended during pregnancy to prevent influenza (flu shot) and pertussis (Tdap vaccine).

Now you may be deciding if you should get the COVID-19 vaccine. This is a personal choice that you should make after talking with your doctor, who is your first point of contact to help you make an informed decision.

What do we know about the COVID-19 vaccine and pregnancy? The two mRNA COVID-19 vaccines, Pfizer BioNTech and Moderna, consist of messenger RNA and use the body’s own cells to generate the coronavirus spike protein, which stimulates immune cells to create antibodies against COVID-19. The third single-dose Janssen (J&J) vaccine, a vector vaccine, uses a harmless adenovirus (a type of virus that causes the common cold) to instruct the body’s cells to make the coronavirus spike protein, training the body's immune system to protect against COVID-19.

While mRNA vaccines are distinct from influenza and Tdap vaccines currently used during pregnancy, mRNA technology has been in development for the last decade.

The COVID-19 vaccines can’t give you COVID-19, as they do not contain the live virus that causes the coronavirus. Also, the mRNA does not enter the cell’s nucleus and does not alter human DNA, so the mRNA vaccines cannot cause any genetic changes, and your body’s cells break down the mRNA quickly.

While the current COVID-19 mRNA vaccines haven’t been studied in pregnant or lactating women, based on how mRNA vaccines work, experts believe they are unlikely to pose a specific risk for people who are pregnant, according to the Centers for Disease Control and Prevention (CDC). Likewise, mRNA vaccines are not thought to be a risk to the breastfeeding infant.

Similarly, experts believe that non-replicating viral vector COVID-19 vaccines are unlikely to pose a risk to the pregnant person or fetus. However, all women younger than age 50 (regardless of whether they are pregnant or recently pregnant) should be aware of the rare risk of thrombocytopenia syndrome (TTS) after receipt of the Janssen (J&J) COVID-19 vaccine.

While safety data on the use of the current COVID-19 vaccines in pregnancy are not currently available, there are also no data to indicate that the vaccines should be contraindicated (not used), and the safety for pregnant people is expected to be similar to non-pregnant people.

While there are still many unknowns, we do know that:

  • Women who are trying to become pregnant do not need to avoid pregnancy after receiving the COVID-19 vaccine.
  • Given the mechanism of action and the safety profile of the vaccine in non-pregnant individuals, COVID-19 vaccines are not thought to cause an increased risk of infertility.
  • If an individual becomes pregnant after the first dose of the COVID-19 vaccine series, the second dose should be administered as indicated.
  • Pregnant people are at increased risk for severe illness from COVID-19. Pregnant people with comorbidities, such as obesity and diabetes, may be at an even higher risk of severe illness.
  • Pregnant people with severe COVID-19 may be at increased risk of adverse pregnancy outcomes, such as preterm birth and pregnancy loss.
  • The side effects that some may experience after receiving the COVID-19 vaccine aren’t expected to be any different for pregnant people. (You may be advised to take acetaminophen if you develop a fever, as fever has been associated with adverse pregnancy outcomes).
  • All vaccine recipients, including pregnant people, should talk with their doctor if they have a history of severe allergic reaction (e.g., anaphylaxis) to any other vaccine or injectable therapy.
  • COVID-19 vaccines should not be administered within 14 days of receipt of another vaccine (such as Tdap and influenza).
  • Pregnant people who decide to get vaccinated should continue to follow the current guidelines to prevent the spread of COVID-19 after they are vaccinated, including wearing a mask, staying at least 6 feet away from others, washing hands often and avoiding crowds.

Pregnant and breastfeeding women need to weigh the potential benefits of vaccination (including preventing COVID-19 illness) against the potential risks regarding vaccination. Ask yourself, what is the risk of virus exposure and not getting vaccinated?

Guidance from the American College of Obstetricians and Gynecologists, Society for Maternal-Fetal Medicine and CDC, advocate for making COVID-19 vaccines available to pregnant and lactating women in consultation with their doctor.

For the latest updates on the COVID-19 vaccine, please check

Are you wondering whether to get the vaccine? Read our blog to learn more.

Edward-Elmhurst Health offers screening options for COVID-19. Eleanor, your personal virtual assistant, can help you check your symptoms 24/7 and advise you on what to do next. We also offer Video Visits and E-Visits for COVID-19 symptoms.

The information in this article may change at any time due to the changing landscape of this pandemic. Read the latest on COVID-19.

HDLife vaccinesCOVIDandflucrop

Protecting yourself from a double whammy of flu and COVID-19

This season, it's important to be prepared for both the flu and COVID-19—and know what you can do to protect yourself...

Read More


What breakthrough infections mean for the COVID-19 vaccine

Do fully-vaccinated people need COVID-19 vaccine boosters?

Read More

COVID vaccine boostercrop

High-risk group now eligible for third COVID-19 vaccine shot

Certain individuals who are moderately to severely immunocompromised are now eligible for an additional (third) dose o...

Read More