A Study to Compare Two Surgical Procedures in Women With BRCA1 Mutations to Assess Reduced Risk of Ovarian Cancer

August 27, 2020
SOROCk
Ovarian Cancer
Samir Undevia, MD

Edward Cancer Center - Naperville
Edward Cancer Center - Plainfield
Nancy Knowles Cancer Center - Elmhurst

This trial studies how well two surgical procedures (bilateral salpingectomy and bilateral salpingo-oophorectomy) work in reducing the risk of ovarian cancer for women with BRCA1 mutations. Bilateral salpingectomy involves the surgical removal of fallopian tubes, and bilateral salpingo-oophorectomy involves the surgical removal of both the fallopian tubes and ovaries. This study may help doctors determine if the two surgical procedures are nearly the same for ovarian cancer risk reduction for women with BRCA1 mutations.

Sponsor: NRG Oncology

https://clinicaltrials.gov/ct2/show/NCT04251052

  • 35-50 years old
  • Declined or elected to defer or are undergoing risk-reducing salpingo-oophorectomy 
  • At least one intact ovary and fallopian tube
  • Positive test results for germline BRCA1 
  • No history of any prior cancer for which the patient received chemotherapy within the past 12 months, hormonal therapy in the past 90 days, or radiotherapy to abdomen or pelvis at any prior time
  • No prior history of ovarian cancer
20 years
Accepting Participants
Interventional
N/A
Amanda Keller, BSN
630-646-6021
630-646-6110
630-646-6072