Preoperative Extended Chemotherapy vs. Chemotherapy Plus Hypofractionated Radiation Therapy For Borderline Resectable Adenocarcinoma of the Head of the Pancreas

October 02, 2017
A021501
Pancreatic Cancer
Alexander Hantel, MD

Edward Cancer Center - Naperville
Edward Cancer Center - Plainfield

The purpose of this study is to compare the effects, good and/or bad, of folfirinox alone with folfirinox and radiation prior to surgery to find out which is better, the same, or worse than the other. 

Sponsor: Alliance for Clinical Trials in Oncology

https://www.clinicaltrials.gov/ct2/show/NCT02839343?term=A021501&recrs=ab&rank=1 

  • Over age of 18
  • Male or female
  • Confirmation of radiographic stage as borderline resectable disease
  • No prior chemotherapy or radiation for pancreatic cancer, no definitive resection of pancreatic cancer
  • No known Gilbert's syndrome or known homozygosity for UGAT1A1*28 polymorphism
  • No uncontrolled gastric ulcer disease
  • Not pregnant and not nursing
 
5 years
Accepting Participants
Interventional
III
Kathy Seymour, BSN
630-646-6075
630-646-6110
630-646-63072