Doctors alerted to rare post-COVID-19 illness in kids

June 01, 2020

The Centers for Disease Control and Prevention (CDC) recently issued a nationwide alert to warn doctors about a rare but dangerous illness in children believed to be linked to COVID-19.

First reported by physicians in the United Kingdom, children of all ages across the United States have been diagnosed with multisystem inflammatory syndrome in children (MIS-C). As of May 11, three children from New York have died so far from the condition (ages 5, 7 and 18) and at least 100 possible cases of MIS-C are under investigation. Chicago area hospitals have reported cases, too.

Some experts believe MIS-C is a post-viral syndrome, or an overreaction by the body’s immune system to COVID-19. Many children affected either had exposure to someone with COVID-19, tested positive for COVID-19 or had positive antibody tests, meaning their immune system had created antibodies in response to the virus.

Preliminary data shows most of the cases are in children between the ages of 5 and 14.

MIS-C shares some traits with toxic shock syndrome and Kawasaki disease, including persistent fever, rashes, red eyes, lips and tongue, and swollen hands and feet.

Kawasaki disease is a rare, non-contagious childhood illness that mainly affects children age 5 and younger, more commonly boys than girls. If left untreated Kawasaki disease can lead to serious heart problems, but with treatment most children fully recover within a few weeks.

Although it produces similar symptoms, MIS-C doesn’t act exactly like Kawasaki disease. MIS-C seems to affect the heart differently and more often results in features consistent with toxic shock.

Although much is still unknown about the relationship of this new syndrome to COVID-19, for now, parents should be aware of the warning signs.

Symptoms of MIS-C are reported to show up several weeks to a month after exposure to the virus, and generally don’t include the typical respiratory symptoms associated with COVID-19.

Parents should be on the lookout for the following symptoms (and act quickly if they’re noticed):

  • Persistent, prolonged high fever (4 days or more)
  • Lethargy
  • Skin rash or discoloration (pale, patchy or blue skin)
  • Red eyes, lips and tongue
  • Swollen hands and feet
  • No appetite, difficulty feeding in infants
  • Abdominal pain, vomiting or diarrhea
  • Racing heart, trouble breathing, chest pain
  • Decreased urination
  • Irritability, confusion

Most children with COVID-19 seem to have mild illness and serious cases remain rare among children. Though uncommon, MIS-C is still a serious complication and some children may become very sick. Prompt treatment is important and may include blood thinners, IV immunoglobulin and corticosteroids.

More information is needed to better understand the new syndrome and its connection to COVID-19.

If parents notice any of the warning signs in their children, they should call the child’s doctor right away or go to the hospital.

Don’t delay child immunizations unless directed by a doctor. Experts highly recommend that children get the required immunizations to protect them from other serious diseases.

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